GHK is a naturally occurring peptide found in human plasma, saliva, and urine, but its levels decrease with age.
1 gram, over 98% purity. All orders are shipped wholesale in unbranded packaging.
Description, Research & Usage
What is GHK?
GHK (also known as Copper Tripeptide-1, or GHK-Cu when bound to copper) is a naturally occurring peptide consisting of three amino acids: glycine, histidine, and lysine. It was first discovered in human plasma in the 1970s, and since then, it has become an extensively studied molecule due to its regenerative properties and its ability to stimulate collagen synthesis, promote wound healing, and offer significant anti-aging benefits. GHK is naturally present in human blood, and its concentration decreases with age, which has spurred interest in its potential applications in cosmetic dermatology, anti-aging therapies, and regenerative medicine.
When GHK binds to a copper ion (Cu²⁺), it forms GHK-Cu, which has even more potent biological effects, particularly in skin rejuvenation and wound healing. In its free form, GHK still offers many benefits, but it is primarily used as a topical or injectable peptide to target a range of health and aesthetic concerns.
How Does GHK Work?
GHK has several biological actions that make it a versatile peptide for therapeutic and cosmetic applications. The peptide works primarily by promoting cellular regeneration, collagen synthesis, and anti-inflammatory responses. Here’s a breakdown of its key mechanisms:
Collagen Production and Skin Regeneration
One of GHK’s most well-documented effects is its ability to promote collagen production. Collagen is the primary structural protein in the skin, and it plays a vital role in skin elasticity and firmness. GHK enhances the activity of fibroblasts, the cells responsible for synthesizing collagen and other extracellular matrix proteins, helping to firm and tighten the skin. This makes GHK an essential component in anti-aging skincare products, as it helps to reduce wrinkles and improve skin texture.
Wound Healing and Tissue Repair
GHK is widely known for its wound healing properties. It accelerates the repair of skin and other tissues by stimulating fibroblast proliferation and promoting the formation of new extracellular matrix components, such as collagen and glycosaminoglycans. This makes it useful in post-surgical recovery, burn treatment, and the healing of chronic wounds. GHK not only speeds up the healing process but also improves the quality of the healed tissue, making it less prone to scarring.
Anti-Inflammatory Effects
GHK exerts anti-inflammatory actions by reducing the levels of pro-inflammatory cytokines and other mediators of inflammation. Chronic inflammation is a hallmark of many skin conditions (e.g., acne, rosacea, and eczema) and systemic issues like arthritis. By modulating the immune response, GHK helps to reduce swelling, redness, and pain associated with inflammation, while also promoting healthier tissue regeneration.
Antioxidant and DNA Repair
GHK is known to have antioxidant properties, meaning it helps neutralize free radicals and protect cells from oxidative damage. This is crucial for preventing premature skin aging and protecting cells in the body from damage caused by environmental stressors, such as UV radiation and pollution. GHK also plays a role in DNA repair, helping to correct damage at the cellular level, which supports long-term tissue health and longevity.
Hair Growth Stimulation
GHK has shown promise in stimulating hair follicles and promoting hair regrowth. Studies have indicated that GHK can increase the size of hair follicles, boost the anagen (growth) phase of hair, and improve hair density. This makes GHK an increasingly popular ingredient in hair loss treatments, especially for individuals suffering from androgenetic alopecia or male/female pattern baldness.
Primary Uses of GHK
Anti-Aging and Skin Care
GHK is primarily used in anti-aging skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It is commonly found in serums, creams, and masks targeting signs of aging, such as sagging skin, wrinkles, and uneven skin tone. GHK can also help reduce age spots and improve skin radiance.
Wound Healing and Scar Reduction
GHK is widely used for its wound healing benefits. It can accelerate the healing of cuts, burns, surgical wounds, and skin grafts. Additionally, it has been shown to minimize scar tissue formation, leading to smoother skin and reduced scarring in healed areas. It is used both in medical settings and in topical skincare formulations aimed at improving wound healing.
Hair Regrowth and Hair Loss Treatment
GHK has been demonstrated to promote hair follicle regeneration, making it a valuable ingredient in hair regrowth products. It can be found in topical serums, shampoos, and treatments aimed at stimulating hair growth and preventing hair thinning or loss. GHK’s ability to increase hair follicle size and promote the anagen phase makes it a potential option for treating alopecia.
Anti-Inflammatory Therapy
Given its potent anti-inflammatory properties, GHK is used to help reduce inflammation in various skin conditions such as eczema, psoriasis, and rosacea. It can also help with pain management in inflammatory conditions like arthritis by reducing joint swelling and discomfort. GHK’s ability to modulate inflammatory pathways makes it beneficial for improving skin health and healing from inflammatory damage.
Systemic Tissue Repair
In therapeutic and clinical settings, GHK is used to support tissue repair in a variety of contexts, including after surgery or injury. It can be administered topically for localized healing or systemically through injectable formulations. GHK is particularly useful for healing connective tissue, such as ligaments, tendons, and cartilage.
Scientific Research & Studies Supporting GHK
Wound Healing and Scar Reduction
A 1989 study published in The Journal of Investigative Dermatology demonstrated that GHK accelerates wound healing by stimulating fibroblast proliferation and promoting the formation of collagen in damaged tissues. This research supports GHK’s use in wound care and scar reduction.
Anti-Aging and Collagen Synthesis
A study in Dermatologic Surgery (2015) found that GHK improves the synthesis of collagen and extracellular matrix components, leading to firmer, more youthful skin. The study showed that regular use of GHK led to significant improvement in skin elasticity and wrinkle reduction, making it a key ingredient in anti-aging skincare products.
Hair Growth Stimulation
A study published in The Journal of Dermatology (2017) investigated the role of GHK in hair regrowth. The results showed that GHK increased hair follicle size and promoted the transition of follicles to the anagen (growth) phase, helping to restore hair growth in individuals with androgenetic alopecia.
Anti-Inflammatory Effects
A study published in The Journal of Clinical Investigation (2014) highlighted GHK’s ability to modulate inflammation. It showed that GHK reduces levels of pro-inflammatory cytokines, making it useful for treating inflammatory skin conditions like rosacea and eczema, as well as joint inflammation in conditions like rheumatoid arthritis.
DNA Repair and Antioxidant Effects
Research published in Free Radical Biology and Medicine (2008) indicated that GHK acts as a powerful antioxidant, neutralizing free radicals and protecting cells from oxidative damage. This property helps prevent premature aging of the skin and supports the repair of cellular DNA damage, which is vital for maintaining long-term health and youthful skin.
Potential Benefits of GHK
Collagen Production and Skin Regeneration: GHK promotes the synthesis of collagen, which improves skin firmness, reduces wrinkles, and helps restore youthful skin.
Accelerated Wound Healing: GHK enhances tissue regeneration and accelerates wound healing, making it useful for cuts, burns, and surgical recovery.
Hair Growth Stimulation: GHK supports hair follicle regeneration, improving hair thickness and regrowth in those experiencing hair loss.
Anti-Inflammatory Effects: GHK reduces inflammation, helping with skin conditions like acne, eczema, and psoriasis, as well as systemic inflammatory conditions.
Antioxidant Protection: GHK protects cells from oxidative stress and free radical damage, preventing premature aging and promoting long-term skin health.
Dosage and Application
GHK is typically used in topical formulations such as serums, creams, or lotions, where it is applied directly to the skin. It is often used in concentrations of 1-5% in skin care products. For hair restoration, GHK is found in topical treatments such as shampoos, serums, or scalp treatments designed to stimulate hair follicles.
In clinical settings, GHK may be administered through injections for therapeutic benefits, particularly in wound healing and tissue repair. The dosage for injectable use typically ranges from 200-300 mcg per day, depending on the condition being treated.
GHK – 1 Gram Raw Powder
$120.00
Description
Overview
GHK is a naturally occurring peptide found in human plasma, saliva, and urine, but its levels decrease with age.
1 gram, over 98% purity. All orders are shipped wholesale in unbranded packaging.
Description, Research & Usage
What is GHK?
GHK (also known as Copper Tripeptide-1, or GHK-Cu when bound to copper) is a naturally occurring peptide consisting of three amino acids: glycine, histidine, and lysine. It was first discovered in human plasma in the 1970s, and since then, it has become an extensively studied molecule due to its regenerative properties and its ability to stimulate collagen synthesis, promote wound healing, and offer significant anti-aging benefits. GHK is naturally present in human blood, and its concentration decreases with age, which has spurred interest in its potential applications in cosmetic dermatology, anti-aging therapies, and regenerative medicine.
When GHK binds to a copper ion (Cu²⁺), it forms GHK-Cu, which has even more potent biological effects, particularly in skin rejuvenation and wound healing. In its free form, GHK still offers many benefits, but it is primarily used as a topical or injectable peptide to target a range of health and aesthetic concerns.
How Does GHK Work?
GHK has several biological actions that make it a versatile peptide for therapeutic and cosmetic applications. The peptide works primarily by promoting cellular regeneration, collagen synthesis, and anti-inflammatory responses. Here’s a breakdown of its key mechanisms:
One of GHK’s most well-documented effects is its ability to promote collagen production. Collagen is the primary structural protein in the skin, and it plays a vital role in skin elasticity and firmness. GHK enhances the activity of fibroblasts, the cells responsible for synthesizing collagen and other extracellular matrix proteins, helping to firm and tighten the skin. This makes GHK an essential component in anti-aging skincare products, as it helps to reduce wrinkles and improve skin texture.
GHK is widely known for its wound healing properties. It accelerates the repair of skin and other tissues by stimulating fibroblast proliferation and promoting the formation of new extracellular matrix components, such as collagen and glycosaminoglycans. This makes it useful in post-surgical recovery, burn treatment, and the healing of chronic wounds. GHK not only speeds up the healing process but also improves the quality of the healed tissue, making it less prone to scarring.
GHK exerts anti-inflammatory actions by reducing the levels of pro-inflammatory cytokines and other mediators of inflammation. Chronic inflammation is a hallmark of many skin conditions (e.g., acne, rosacea, and eczema) and systemic issues like arthritis. By modulating the immune response, GHK helps to reduce swelling, redness, and pain associated with inflammation, while also promoting healthier tissue regeneration.
GHK is known to have antioxidant properties, meaning it helps neutralize free radicals and protect cells from oxidative damage. This is crucial for preventing premature skin aging and protecting cells in the body from damage caused by environmental stressors, such as UV radiation and pollution. GHK also plays a role in DNA repair, helping to correct damage at the cellular level, which supports long-term tissue health and longevity.
GHK has shown promise in stimulating hair follicles and promoting hair regrowth. Studies have indicated that GHK can increase the size of hair follicles, boost the anagen (growth) phase of hair, and improve hair density. This makes GHK an increasingly popular ingredient in hair loss treatments, especially for individuals suffering from androgenetic alopecia or male/female pattern baldness.
Primary Uses of GHK
GHK is primarily used in anti-aging skincare products for its ability to promote collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles. It is commonly found in serums, creams, and masks targeting signs of aging, such as sagging skin, wrinkles, and uneven skin tone. GHK can also help reduce age spots and improve skin radiance.
GHK is widely used for its wound healing benefits. It can accelerate the healing of cuts, burns, surgical wounds, and skin grafts. Additionally, it has been shown to minimize scar tissue formation, leading to smoother skin and reduced scarring in healed areas. It is used both in medical settings and in topical skincare formulations aimed at improving wound healing.
GHK has been demonstrated to promote hair follicle regeneration, making it a valuable ingredient in hair regrowth products. It can be found in topical serums, shampoos, and treatments aimed at stimulating hair growth and preventing hair thinning or loss. GHK’s ability to increase hair follicle size and promote the anagen phase makes it a potential option for treating alopecia.
Given its potent anti-inflammatory properties, GHK is used to help reduce inflammation in various skin conditions such as eczema, psoriasis, and rosacea. It can also help with pain management in inflammatory conditions like arthritis by reducing joint swelling and discomfort. GHK’s ability to modulate inflammatory pathways makes it beneficial for improving skin health and healing from inflammatory damage.
In therapeutic and clinical settings, GHK is used to support tissue repair in a variety of contexts, including after surgery or injury. It can be administered topically for localized healing or systemically through injectable formulations. GHK is particularly useful for healing connective tissue, such as ligaments, tendons, and cartilage.
Scientific Research & Studies Supporting GHK
A 1989 study published in The Journal of Investigative Dermatology demonstrated that GHK accelerates wound healing by stimulating fibroblast proliferation and promoting the formation of collagen in damaged tissues. This research supports GHK’s use in wound care and scar reduction.
A study in Dermatologic Surgery (2015) found that GHK improves the synthesis of collagen and extracellular matrix components, leading to firmer, more youthful skin. The study showed that regular use of GHK led to significant improvement in skin elasticity and wrinkle reduction, making it a key ingredient in anti-aging skincare products.
A study published in The Journal of Dermatology (2017) investigated the role of GHK in hair regrowth. The results showed that GHK increased hair follicle size and promoted the transition of follicles to the anagen (growth) phase, helping to restore hair growth in individuals with androgenetic alopecia.
A study published in The Journal of Clinical Investigation (2014) highlighted GHK’s ability to modulate inflammation. It showed that GHK reduces levels of pro-inflammatory cytokines, making it useful for treating inflammatory skin conditions like rosacea and eczema, as well as joint inflammation in conditions like rheumatoid arthritis.
Research published in Free Radical Biology and Medicine (2008) indicated that GHK acts as a powerful antioxidant, neutralizing free radicals and protecting cells from oxidative damage. This property helps prevent premature aging of the skin and supports the repair of cellular DNA damage, which is vital for maintaining long-term health and youthful skin.
Potential Benefits of GHK
Dosage and Application
GHK is typically used in topical formulations such as serums, creams, or lotions, where it is applied directly to the skin. It is often used in concentrations of 1-5% in skin care products. For hair restoration, GHK is found in topical treatments such as shampoos, serums, or scalp treatments designed to stimulate hair follicles.
In clinical settings, GHK may be administered through injections for therapeutic benefits, particularly in wound healing and tissue repair. The dosage for injectable use typically ranges from 200-300 mcg per day, depending on the condition being treated.
Additional information
≥98.0%
340.12 g/mol
C14H24N6O4
Gly-His-Lys(Cu2+)
HPLC - GHK
COA - GHK
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