Research Articles

In recent years, the field of weight management has seen remarkable advances with the introduction of GLP-1 peptide drugs like semaglutide and tirzepatide. As the search for effective weight loss solutions continues, scientists are now investigating “exercise mimetics” — compounds that replicate the effects of exercise without requiring actual physical activity.  One such new compound […]

GLP-1 peptides are becoming increasingly popular for weight management. However, researchers and clinicians have observed an unexpected side effect: many people report dramatically reduced alcohol cravings and intake while taking these medications. This emerging evidence has sparked interest in the potential application of GLP-1 agonists for treating alcohol use disorder (AUD), a condition affecting millions […]

In recent years, GLP-1 receptor agonists like semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound) have revolutionized weight management and diabetes treatment.  One of the ways these peptides work is by combatting what’s known as food noise: intrusive thoughts related to food.  Emerging evidence suggests that GLP-1 peptides are effective at reducing food noise, providing both physiological and […]

People interested in peptide research are bound to come across the name “Khavinson” at some point. A prolific Russian scientist, Khavinson specialized in anti-aging applications of peptides. He spent over four decades studying and developing peptide therapies, publishing hundreds of papers and developing dozens of peptide products in the process. Here’s everything you need to […]

In peptide therapy and research, “stacking” refers to combining multiple peptides to enhance their effects synergistically. In the context of stacking GLP-1s, that means combining two weight-loss peptides like semaglutide and cagrilintide for even greater effects. In the words of researchers, “combining obesity medications with different mechanisms of action might be beneficial for individuals with […]

Growth hormone secretagogues (GH secretagogues) are artificial compounds that stimulate the body’s natural production and release of growth hormone. They can impart benefits like improved sleep, energy, skin, and exercise recovery.  Unlike synthetic growth hormone, these peptides work by boosting the body’s natural GH production. GH secretagogues like ipamorelin have been used by athletes for […]

Split dosing refers to dividing a single GLP-1 weight loss peptide dose into multiple doses. For example,  a patient taking 2.5 mg of tirzepatide per week might split that dose into 1.25 mg on Monday and 1.25 mg on Thursday.  Similar to microdosing GLP-1s, split-dosing is sometimes done to: Reduce potential side effects like nausea […]

Microdosing GLP-1 peptides is a new trend in weight loss circles. It’s growing in popularity thanks to perceived benefits like a lower risk of side effects and preserving muscle mass. But is microdosing worth it? And what kind of doses are used? Short answer: yes, microdosing can help minimize side effects while still promoting weight […]

Weight loss peptides are growing incredibly popular. Tirzepatide (Mounjaro/Zepbound) in particular has become one of the most popular peptides for weight loss, but there are many newer generation peptides coming out as well.  One such new-generation peptide is survodutide, which works through slightly different mechanisms. Let’s break down what these peptides are and wghat the […]